First released in 2004, the Guide is a joint publication of CITC and the Tuberculosis Control Branch of the California Department of Public Health. It contains information and user-friendly tools and templates for use by any clinician who participates in the management of patients with drug-resistant TB. 
The 10 chapters and 4 appendices cover major topics pertaining to epidemiology, diagnosis, laboratory issues, treatment, medications, pediatrics, co-morbidities and special situations, monitoring and case management, adverse reactions, and treatment of contacts.