Treating Latent Tuberculosis Infection in High-Risk Populations

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These tools are primarily for urban TB programs wishing to improve secondary prevention of TB in those groups at highest risk of progression to TB disease, including the homeless, chemically dependent and mentally ill. TB control staff are able to:

  • Understand the background and rationale for DOT of Latent TB Infection (LTBI)
  • Learn about the San Francisco Tuberculosis Outreach and Prevention Program and other successful models
  • Outline the essential components for a successful program with high completion rates
  • Build a DOT team
  • Build community collaboration

The materials include sample protocols, forms, and job descriptions.

Please note:  This toolbox contains information about the treatment of latent tuberculosis infection (LTBI). It was produced prior to the release of updated guidelines from the CDC in February 2020.  For the most current guidance available regarding LTBI treatment, please see: Guidelines for the Treatment of Latent Tuberculosis Infection: Recommendations from the National Tuberculosis Controllers Association and CDC, 2020

Date of Release:  January 2005