University of California San Francisco

Chapter 3. Laboratory

Chapter cover
General information on TB laboratory work
- Communication between clinician and laboratory
- How should specimens be collected?
Microscopy, culture identification, and growth-based testing
Critical concentration and minimum inhibitory concentration (MIC)
- Critical concentrations
- MIC-when to order and how to interpret
At-a Glance: Drug susceptibility testing available at 5 U.S. referral laboratories (2022 version)
- 2026 update, Excel DST services at select U.S. referral laboratories: A tool for clinicians (Please check often for updates)
Molecular methods for detection of M. tuberculosis complex DNA and drug resistance mutations
- Genes associated with drug resistance
- Molecular tests for drug resistance
Therapeutic drug monitoring (TDM)
National TB Molecular Surveillance
References

Product

Drug-Resistant Tuberculosis: A Survival Guide for Clinicians, 3rd edition / 2022 Updates

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Available Now! DST Services at Select U.S. Referral Labs: A Tool for Clinicians

Phenotypic and molecular drug susceptibility testing (DST) available at select referral laboratories has been fully updated. Developed in partnership with national referral laboratory colleagues, the tool is an Excel file that contains detailed information for clinicians about the DST services available at 7 key referral laboratories in the U.S.

lab tools from at a glance and CDC pages