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Chapter 9. Adverse Reactions

  • Introduction
  • Gastrointestinal
    • Nausea and vomiting
    • Diarrhea
    • Hepatotoxicity
  • Dermatologic reactions
    • Maculopapular rash and pruritus
    • Flushing reactions
    • Photosensitivity and hyperpigmentation
    • Lichenoid drug reactions
    • Hives and urticarial
    • Table: Drug rechallenge
    • Table: Oral desensitization
  • Severe drug reactions
    • Systemic reactions
    • Drug reaction with eosinophilia and systemic symptoms (DRESS)
    • RIF hypersensitivity reactions
  • Hematologic abnormalities
  • Neurotoxicity
    • Peripheral neuropathy
    • Central nervous system toxicity
    • Psychiatric effects
    • Seizures
    • Serotonin syndrome
  • Musculoskeletal adverse effects
    • Myalgias and arthralgias
    • Tendonitis and tendon rupture
  • Cardiovascular toxicity and adverse reactions
    • QT interval prolongation
    • Aortic aneurysm or dissection
  • Ophthalmic toxicity
    • Prevention and monitoring
    • Retrobulbar neuritis
    • Uveitis
  • Ototoxicity (eighth nerve toxicity)
    • Vestibular toxicity
    • Auditory toxicity
  • Nephrotoxicity
    • Prevention and monitoring
    • Electrolyte loss
  • Miscellaneous adverse reactions
    • Hypothyroidism
    • Metallic taste
    • Gynecomastia
    • Alopecia
    • Superficial fungal infection
    • Black hairy tongue
    • Non-specific numbness
    • Hypo-/Hyperglycemia
  • References
Product
Drug-Resistant Tuberculosis: A Survival Guide for Clinicians, 3rd edition / 2022 Updates
  • Front Matter
  • Chapter 1. Epidemiology & Background
  • Chapter 2. Diagnosis
  • Chapter 3. Laboratory
  • Chapter 4. Treatment
  • Chapter 5. Medication Fact Sheets
  • Chapter 6. Pediatrics
  • Chapter 7. Co-morbidities & Special Situations
  • Chapter 8. Monitoring & Case Management
  • Chapter 9. Adverse Reactions
  • Chapter 10. Contacts
  • Appendix 1: Expert Resources

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In-Person TB Trainings 

Focus on LTBI
Date: October 12, 2026 (Mon)
Oakland, CA
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Tuberculosis Clinical Intensive
Date: October 13-15, 2026 (Tue-Thu)
Oakland, CA
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